Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) Kits ELISA

Human Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. The suppression of NHE1 (Montrer SLC9A1 Kits ELISA) in esophageal squamous cell carcinoma (ESCC) may enhance malignant potential by mediating PI3K (Montrer PIK3CA Kits ELISA)-AKT (Montrer AKT1 Kits ELISA) signaling and epithelial-mesenchymal transition via Notch (Montrer NOTCH1 Kits ELISA) signaling, and may be related to a poor prognosis in patients with ESCC.

2. Genetic disruption of the intracellular pH-regulating proteins Na+/H+ exchanger 1 (SLC9A1 (Montrer SLC9A1 Kits ELISA)) and carbonic anhydrase 9 (Montrer CA9 Kits ELISA) reduces the proliferation of colon cancer cells.

3. Hypoxia-induced MCT1 (Montrer CMA1 Kits ELISA) supports glioblastoma glycolytic phenotype, being responsible for lactate efflux and an important mediator of cell survival and aggressiveness

4. NHE1 (Montrer SLC9A1 Kits ELISA) mutation is associated with metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer.

5. our finding that the expression of MCT1 (Montrer CMA1 Kits ELISA) and MCT4 is reduced in mutant IDH1 (Montrer IDH1 Kits ELISA) gliomas highlights the unusual metabolic reprogramming that occurs in mutant IDH1 (Montrer IDH1 Kits ELISA) tumors and has important implications for our understanding of these tumors and their treatment

6. The expression pattern of sNHE suggested that this protein may be involved in the regulation of sperm motility, and aberration of its expression in sperm may contribute to the pathogenesis of asthenozoospermia.

7. MCT1 (Montrer CMA1 Kits ELISA) expression, independent of transporter activity, is required for growth factor-induced tumor cell motility.

8. TOMM20 (Montrer TOMM20 Kits ELISA), MCT1 (Montrer CMA1 Kits ELISA), and MCT4 expression was significantly different in Hodgkin and Reed Sternberg (HRS) cells. HRS have high expression of MCT1 (Montrer CMA1 Kits ELISA), while tumor associated macrophages have absent MCT1 (Montrer CMA1 Kits ELISA) expression. Tumor-infiltrating lymphocytes have absent MCT1 (Montrer CMA1 Kits ELISA) expression. Reactive lymph nodes in contrast to cHL (Montrer CHRDL1 Kits ELISA) tumors had low TOMM20 (Montrer TOMM20 Kits ELISA), MCT1 (Montrer CMA1 Kits ELISA), and MCT4 expression in lymphocytes and macrophages.

9. TOMM20 (Montrer TOMM20 Kits ELISA) and MCT1 (Montrer CMA1 Kits ELISA) were highly expressed in diffuse large B-cell lymphoma lymphocytes, indicating an OXPHOS phenotype, whereas non-neoplastic lymphocytes in the control samples did not express these markers.

10. Data show for the first time that PRLR (Montrer PRLR Kits ELISA) activation stimulates breast cancer cell invasiveness via the activation of NHE1 (Montrer SLC9A1 Kits ELISA). Data propose that PRL (Montrer PRL Kits ELISA)-induced NHE1 (Montrer SLC9A1 Kits ELISA) activation and the resulting NHE1 (Montrer SLC9A1 Kits ELISA)-dependent invasiveness may contribute to the metastatic behavior of human breast cancer cells.

Zebrafish Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. Data indicate that monocarboxylate transporters (MCTs1 (Montrer MCTS1 Kits ELISA)-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Horse (Equine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. The expression of monocarboxylic acid transporter 1 (MCT1 (Montrer MCTS1 Kits ELISA)), MCT2 (Montrer SLC16A7 Kits ELISA), and CD147 in 3 horse breeds with different atheletic demands is reported.[MCT1 (Montrer MCTS1 Kits ELISA); MCT2 (Montrer SLC16A7 Kits ELISA)]

2. Results indicated that a single IET resulted in transient increases in MCT1 (Montrer MCTS1 Kits ELISA) and MCT4 (Montrer SLC16A3 Kits ELISA) mRNA expression and protein content in untrained and trained horses.

3. The coding sequence of MCT1 (Montrer MCTS1 Kits ELISA), MCT4 (Montrer SLC16A3 Kits ELISA), and CD147 in healthy horses, and the incidence of polymorphisms of these proteins in horses with excercise-induced myopathy are reported.

4. MCT1 (Montrer MCTS1 Kits ELISA) protein content in GMM samples obtained when the horses were 24 months old was significantly higher than at 2 months of age. However, MCT4 (Montrer SLC16A3 Kits ELISA) protein content remained unchanged throughout the study period.

Mouse (Murine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. Silencing or genetic deletion of MCT1 (Montrer MCTS1 Kits ELISA) in vivo inhibited migration, invasion, and spontaneous metastasis.

2. It was concluded that both MCT1 (Montrer MCTS1 Kits ELISA) and CAII (Montrer CA2 Kits ELISA) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1 (Montrer MCTS1 Kits ELISA)(+/-) mice remain unexplained.

3. Exercise-induced changes in tumour LDH-B (Montrer LDHB Kits ELISA) and MCT1 (Montrer MCTS1 Kits ELISA) expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

4. Chronic lactate administration after exercise increases MCT1 (Montrer MCTS1 Kits ELISA) protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (Montrer GYS1 Kits ELISA) storage after exercise training.

5. This study showed that mouse MCT1 (Montrer MCTS1 Kits ELISA), MCT2 (Montrer SLC16A7 Kits ELISA), and MCT4 (Montrer SLC16A3 Kits ELISA) are expressed in the PNS. While DRG neurons express MCT1 (Montrer MCTS1 Kits ELISA), myelinating Schwann cells.

6. These data for the first time demonstrate that MCT1 (Montrer MCTS1 Kits ELISA) is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

7. in Parkinson's disease, the levels of MCT1 (Montrer MCTS1 Kits ELISA), MCT2 (Montrer SLC16A7 Kits ELISA) and GLUT1 (Montrer SLC2A1 Kits ELISA) is not changed following dopaminergic neurodegeneration

8. results suggest that a reduction in mitochondria is a result, rather than the cause, of the metabolic deficiency observed in Basigin-null mice, and likely occurs because of reduced metabolic activity in the absence of MCT1 (Montrer MCTS1 Kits ELISA) expression.

9. miR (Montrer MLXIP Kits ELISA)-29a, miR (Montrer MLXIP Kits ELISA)-29b selectively target MCT1 (Montrer MCTS1 Kits ELISA) 3'UTR (Montrer UTS2R Kits ELISA) ; the miR (Montrer MLXIP Kits ELISA)-29 isoforms are highly expressed in islets and contribute to silencing Mct1 (Montrer MCTS1 Kits ELISA) in beta cells; miR (Montrer MLXIP Kits ELISA)-29 isoforms contribute to beta-cell-specific silencing of the MCT1 (Montrer MCTS1 Kits ELISA) transporter and may affect insulin (Montrer INS Kits ELISA) release

10. monocarboxylate transporter 1 (MCT1), is highly enriched within oligodendroglia and disruption of this transporter produces axon damage and neuron loss in animal and cell culture models; in addition, this same transporter is reduced in patients with, and in mouse models of, amyotrophic lateral sclerosis, suggesting a role for oligodendroglial MCT1 (Montrer MCTS1 Kits ELISA) in pathogenesis

Cow (Bovine) Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1) interaction partners

1. This study confirmed age-dependent changes of MCT1 (Montrer MCTS1 Kits ELISA) expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

2. These findings show that MCT 1 (Montrer MCTS1 Kits ELISA) increases with the development of rumen function and also in adult animals MCT 1 (Montrer MCTS1 Kits ELISA) may change with the feeding.

3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.