PAK1 anticorps (pSer204)
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- Antigène Voir toutes PAK1 Anticorps
- PAK1 (P21-Activated Kinase 1 (PAK1))
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Épitope
- pSer204
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- The antibody detects endogenous levels of PAK1 only when phosphorylated at serine 204.
- Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- PAK1 (phospho Ser204) antibody was raised against a peptide sequence around phosphorylation site of Serine 204 (T-R-S (p)-V-I) derived from Human PAK1.
- Isotype
- IgG
- Top Product
- Discover our top product PAK1 Anticorps primaire
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- Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Antigène
- PAK1 (P21-Activated Kinase 1 (PAK1))
- Autre désignation
- PAK1 (PAK1 Produits)
- Synonymes
- anticorps X-PAK1, anticorps XPak1, anticorps pak, anticorps pak-1, anticorps pakalpha, anticorps PAKalpha, anticorps AW045634, anticorps PAK-1, anticorps Paka, anticorps p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog, anticorps p21 (RAC1) activated kinase 1, anticorps p21 protein (Cdc42/Rac)-activated kinase 1, anticorps Serine/threonine-protein kinase pak-1, anticorps pak1.S, anticorps PAK1, anticorps Pak1, anticorps pak-1
- Sujet
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
- Poids moléculaire
- 65 kDa
- ID gène
- 5058
- NCBI Accession
- NP_002567
- UniProt
- Q13153
- Pathways
- Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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