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p53 anticorps (C-Term)

Name: p53 anticorps (C-Term)
SKU: ABIN184159
Price: 180.78 EUR
Availability: InStock

TP53 Reactivité: Humain, Rat, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated

WB Suggested Anti-TP53 Antibody Titration: 0. (p53 anticorps (C-Term))

Rabbit Anti-TP53 antibody Catalog Number: AVARP02055 Paraffin Embedded Tissue: Human Lung cell Cellular Data: bronchiole epithelium of renal tubule Antibody Concentration: 4. (p53 anticorps (C-Term))

IHC

2 images

N° du produit ABIN184159

Fiche de données

Antigène Voir toutes p53 (TP53) Anticorps

p53 (TP53) (Tumor Protein P53 (TP53))
Épitope
49

39

39

38

32

28

24

24

23

22

21

20

19

19

18

18

16

16

14

13

9

8

8

8

8

8

7

7

7

7

7

7

6

6

6

5

5

5

5

4

4

4

3

3

3

3

3

3

3

3
C-Term
Reactivité
864

264

218

113

48

35

33

19

10

8

8

6

4

3

3

3

2

2

2

2

1

1

1

1
Humain, Rat, Cheval
Hôte
648

230

6

2

1
Lapin
Anticorps secondaires appropriés
Clonalité
601

285

1
Polyclonal
Conjugué
485

48

37

26

25

25

24

24

22

22

22

13

13

13

13

13

12

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Cet anticorp p53 est non-conjugé
Application
696

323

246

217

194

140

124

119

119

65

53

35

20

17

13

12

12

9

9

8

6

4

3

3

2

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Séquence

RELNEALELK DAQAGKEPGG SRAHSSHLKS KKGQSTSRHK KLMFKTEGPD

Homologie

Horse: 93%, Human: 100%, Rat: 92%

Attributs du produit

This is a rabbit polyclonal antibody against TP53. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Protein A purified

Immunogène

The immunogen is a synthetic peptide directed towards the C terminal region of human TP53

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Indications d'application

Optimal working dilutions should be determined experimentally by the investigator.

Commentaires

Antigen size: 393 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freeze-thaw cycles.

Stock

-20 °C

Stockage commentaire

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antigène

p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation

TP53 (TP53 Produits)

Synonymes

anticorps BCC7, anticorps LFS1, anticorps P53, anticorps TRP53, anticorps p53, anticorps Trp53, anticorps brp53, anticorps drp53, anticorps etID22686.5, anticorps fb40d06, anticorps wu:fb40d06, anticorps zgc:111919, anticorps Tp53, anticorps bbl, anticorps bfy, anticorps bhy, anticorps p44, anticorps tp53, anticorps Xp53, anticorps TP53, anticorps tumor protein p53, anticorps cellular tumor antigen p53, anticorps transformation related protein 53, anticorps tumor protein p53 L homeolog, anticorps TP53, anticorps CpipJ_CPIJ002758, anticorps Tp53, anticorps tp53, anticorps Trp53, anticorps tp53.L

Sujet

TP53 acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
Alias Symbols: P53, LFS1, TRP53
Protein Size: 393

Poids moléculaire

44 kDa

ID gène

7157

NCBI Accession

NM_000546, NP_000537

UniProt

P04637

Pathways

Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg