Insulin anticorps
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- Antigène Voir toutes Insulin (INS) Anticorps
- Insulin (INS)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Insulin est non-conjugé
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Application
- ELISA
- Specificité
- The site of connection of C-peptide and C-end of B-chain of proinsulin molecule. MAbs 1D6 and 1D3 react with different epitopes on human proinsulin molecule, both of each are generated by the interactions between insulin and C-peptide parts of prohormone. Kd MAb 3A1 is 1.1 x 10-8 M. Kd MAb 1G4 is 2.6 x 10-7 M. Kd MAb 1D6 and 1D3 is >3 x 10-8 M. Kd MAb 7D6 is >5 x 10-8 M. MAbs 3A1, 1G4, 1D6, 1D3 and 7D6 do not cross-react with human, bovine and porcine insulin, bovine and porcine proinsulin, and human C-peptide.
- Purification
- Protein A purified
- Immunogène
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Purified human proinsulin.
Type of Immunogen: Purified protein - Clone
- 1D3
- Isotype
- IgG1
- Top Product
- Discover our top product INS Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- avoid freezing
- Stock
- 4 °C
- Stockage commentaire
- 4°C, avoid freezing.
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- Antigène
- Insulin (INS)
- Autre désignation
- Insulin (INS Produits)
- Synonymes
- anticorps IDDM2, anticorps ILPR, anticorps IRDN, anticorps MODY10, anticorps ins1, anticorps xins, anticorps ins1-a, anticorps Insulin, anticorps AA986540, anticorps Ins-2, anticorps InsII, anticorps Mody, anticorps Mody4, anticorps proinsulin, anticorps zgc:109842, anticorps igf2-A, anticorps ins, anticorps ins-a, anticorps ins-b, anticorps insulin, anticorps insulin precursor, anticorps insulin II, anticorps preproinsulin, anticorps insulin L homeolog, anticorps insulin S homeolog, anticorps INS, anticorps INS-IGF2, anticorps ins, anticorps Ins, anticorps PIN, anticorps Ins2, anticorps ins.L, anticorps ins.S
- Sujet
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Name/Gene ID: INS
Family: Hormone
Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin - ID gène
- 3630
- UniProt
- P01308
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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