ATF4 anticorps (pSer245)

N° du produit ABIN3020091

Détail du produit anti-ATF4 anticorps

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Épitope: pSer245

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S245 of human ATF4

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATF4

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Autre désignation: ATF4 (ATF4 Produits)

Synonymes: anticorps CREB-2, anticorps CREB2, anticorps TAXREB67, anticorps TXREB, anticorps ATF4, anticorps atf-4, anticorps creb-2, anticorps creb2, anticorps taxreb67, anticorps txreb, anticorps atf4, anticorps wu:fj01c08, anticorps wu:fk30b04, anticorps zgc:85951, anticorps sb:eu681, anticorps wu:fb08f07, anticorps zgc:171702, anticorps Atf-4, anticorps C/ATF, anticorps ATF4-I, anticorps atf4-a, anticorps atf4-b, anticorps atf4-ii, anticorps activating transcription factor 4, anticorps activating transcription factor 4 L homeolog, anticorps activating transcription factor 4a, anticorps activating transcription factor 4b, anticorps activating transcription factor 4 S homeolog, anticorps ATF4, anticorps atf4, anticorps Atf4, anticorps atf4.L, anticorps atf4a, anticorps atf4b, anticorps atf4.S

Sujet: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.,ATF4,CREB-2,CREB2,TAXREB67,TXREB,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Protein folding,Protein phosphorylation,ATF4

Poids moléculaire: 38 kDa

ID gène: 468

UniProt: P18848

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response