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PAK1 anticorps (AA 1-240)
PAK1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3023361
Détail du produit anti-PAK1 anticorps
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Antigène
Voir toutes PAK1 Anticorps
PAK1
(P21-Activated Kinase 1 (PAK1))
Épitope
Tous les épitopes à travers PAK1 Anticorps.
AA 1-240
Reactivité
Toutes les réactivités sur PAK1 Anticorps
Humain
Hôte
Toutes les hôtes sur PAK1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur PAK1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PAK1 Anticorps
Cet anticorp PAK1 est non-conjugé
Application
Tous les applications à travers PAK1 Anticorps.
Western Blotting (WB)
Séquence
MSNNGLDIQD KPPAPPMRNT STMIGAGSKD AGTLNHGSKP LPPNPEEKKK KDRFYRSILP GDKTNKKKEK ERPEISLPSD FEHTIHVGFD AVTGEFTGMP EQWARLLQTS NITKSEQKKN PQAVLDVLEF YNSKKTSNSQ KYMSFTDKSA EDYNSSNALN VKAVSETPAV PPVSEDEDDD DDDATPPPVI APRPEHTKSV YTRSVIEPLP VTPTRDVATS PISPTENNTT PPDALTRNTE
Réactivité croisée
Humain, Souris, Rat
Attributs du produit
Polyclonal Antibodies
Immunogène
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PAK1 (NP_002567.3).
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Stockage
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Références pour anticorps anti-PAK1 (ABIN3023361)
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Tu, Wang, Cui, Wang, Ran, Bao, Lu, Wang, Lydon, DeMayo, Zhang, Kong, Wu, Wang : "Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice. " dans: Cell death and differentiation , Vol. 23 , Issue 1 , pp. 169-81 , (2016 ) (PubMed ).
Détails sur PAK1
(cache)
Antigène
PAK1
(P21-Activated Kinase 1 (PAK1))
Autre désignation
PAK1 (PAK1 Produits )
Synonymes
anticorps X-PAK1, anticorps XPak1, anticorps pak, anticorps pak-1, anticorps pakalpha, anticorps PAKalpha, anticorps AW045634, anticorps PAK-1, anticorps Paka, anticorps p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog, anticorps p21 (RAC1) activated kinase 1, anticorps p21 protein (Cdc42/Rac)-activated kinase 1, anticorps Serine/threonine-protein kinase pak-1, anticorps pak1.S, anticorps PAK1, anticorps Pak1, anticorps pak-1
Sujet
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PAK1,PAKalpha,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,PAK1
Poids moléculaire
60 kDa/61 kDa
ID gène
5058
UniProt
Q13153
Pathways
Signalisation MAPK , Signalisation RTK , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Skeletal Muscle Fiber Development , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , Embryonic Body Morphogenesis
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