Prothrombin anticorps (C-Term)

N° du produit ABIN3042926

Détail du produit anti-Prothrombin anticorps

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Épitope: AA 600-612, C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prothrombin est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Prothrombin(F2) detection. Tested with WB in Rat.

Séquence: THVFRLKRWM QKV

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Prothrombin(F2) detection. Tested with WB in Rat.
Gene Name: coagulation factor II(thrombin)
Protein Name: Prothrombin

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin(600-612aa THVFRLKRWMQKV).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-Prothrombin (ABIN3042926)

Shen, Fang, Lv, Pei, Wang, Jiang, Ding: "Heparin impairs angiogenesis through inhibition of microRNA-10b." dans: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2 (F2 Produits)

Synonymes: anticorps PT, anticorps RPRGL2, anticorps THPH1, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps zgc:66319, anticorps wu:fb57c10, anticorps wu:fd42e09, anticorps wu:fd59d01, anticorps prothrombin, anticorps F2, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, anticorps coagulation factor II (thrombin), anticorps F2, anticorps f2

Sujet: F2(Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al.(1987) assigned the gene for human prothrombin(F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by activating protein C.

Synonyms: coagulation factor II(thrombin) antibody|Coagulation factor II antibody|Coagulation factor II precursor antibody|Coagulation factor II thrombin antibody|Dysprothrombinemia antibody|EC 3.4.21.5 antibody|F 2 antibody|F2 antibody|Factor II antibody|Hyperprothrombinemia antibody|Hypoprothrombinemia antibody|Prepro coagulation factor II antibody|Prothrombin antibody|Prothrombin B chain antibody|prothrombin B-chain antibody|PT antibody|RPRGL2 antibody|Serine protease antibody|THPH1 antibody|THRB antibody|THRB_HUMAN antibody|Thrombin antibody|Thrombin heavy chain antibody

UniProt: P18292

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling