Insulin anticorps

N° du produit ABIN356469

Détail du produit anti-Insulin anticorps

Antigène: Insulin (INS)

Reactivité: Humain, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Insulin est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Insulin.
Cellular Localization: Cytoplasmic.

Purification: Protein A Chromatography.

Immunogène: Purified human insulin conjugated to carrier protein.

Isotype: IgG

Information d'application

Indications d'application: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears). For IHC dilute concentared antibody at 1/50-1/100 using streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. Immunofluorescence. Recommended Positive Control: Human pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Insulin

Antigène: Insulin (INS)

Autre désignation: Insulin (INS Produits)

Synonymes: anticorps IDDM2, anticorps ILPR, anticorps IRDN, anticorps MODY10, anticorps ins1, anticorps xins, anticorps ins1-a, anticorps Insulin, anticorps AA986540, anticorps Ins-2, anticorps InsII, anticorps Mody, anticorps Mody4, anticorps proinsulin, anticorps zgc:109842, anticorps igf2-A, anticorps ins, anticorps ins-a, anticorps ins-b, anticorps insulin, anticorps insulin precursor, anticorps insulin II, anticorps preproinsulin, anticorps insulin L homeolog, anticorps insulin S homeolog, anticorps INS, anticorps INS-IGF2, anticorps ins, anticorps Ins, anticorps PIN, anticorps Ins2, anticorps ins.L, anticorps ins.S

Sujet: Insulin is a 51 amino acids peptide hormone MW 5808 Da. It is produced by beta cells of the islets of Langerhans in the pancreas. Insulin enhances membrane transport of glucose, amino acids and certain ions. It promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Lack of insulin causes diabetes mellitus. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS

ID gène: 3630

NCBI Accession: NP_000198

UniProt: P01308

Pathways: Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation