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p53 anticorps (AA 14-389) (FITC)

TP53 Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache), Chien, Poulet, Chinese Hamster, Hamsters dorés syriens IF, FACS, ICC Hôte: Souris Monoclonal PAb240 FITC

N° du produit ABIN4880089

Fiche de données

Antigène Voir toutes p53 (TP53) Anticorps

p53 (TP53) (Tumor Protein P53 (TP53))
Épitope
50

40

39

38

32

28

26

24

23

23

22

20

20

20

18

18

16

16

14

13

10

9

9

9

9

7

7

7

7

7

7

7

6

6

6

5

5

5

5

4

4

4

3

3

3

3

3

3

3

3
AA 14-389
Reactivité
879

269

221

112

47

34

33

18

10

8

8

6

4

4

3

3

2

2

1

1

1

1

1

1
Humain, Souris, Rat, Singe, Boeuf (Vache), Chien, Poulet, Chinese Hamster, Hamsters dorés syriens
Hôte
663

230

6

2

1

1
Souris
Anticorps secondaires appropriés
Clonalité
611

291

1
Monoclonal
Conjugué
501

49

36

26

25

25

24

24

22

22

22

13

13

13

13

13

12

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Cet anticorp p53 est conjugé à/à la FITC
Application
710

328

249

217

200

145

124

123

119

65

55

35

20

17

13

12

12

10

9

8

6

4

3

3

2

2

2

2

1

1

1

1

1
Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificité

This antibody recognises cellular tumour antigen p53, a 50 kDa transcription factor and major tumour suppressor that plays a major role in regulating cellular responses to DNA damage and other genomic aberrations. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. The Pab240 antibody recognizes an epitope between amino acids 156-214 on murine p53.

Purification

Purified on protein A from tissue culture supernatant.

Immunogène

Purified p53-b-galactosidase fusion protein containing p53 sequence from amino acids 14-389

Clone

PAb240

Isotype

IgG1

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Indications d'application

Optimal antibody dilution should be determined by titration

Commentaires

Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the Sp2/0-Ag.14 myeloma cell line

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link®, supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Antigène

p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation

P53 (TP53 Produits)

Synonymes

anticorps BCC7, anticorps LFS1, anticorps P53, anticorps TRP53, anticorps p53, anticorps Trp53, anticorps brp53, anticorps drp53, anticorps etID22686.5, anticorps fb40d06, anticorps wu:fb40d06, anticorps zgc:111919, anticorps Tp53, anticorps bbl, anticorps bfy, anticorps bhy, anticorps p44, anticorps tp53, anticorps Xp53, anticorps TP53, anticorps tumor protein p53, anticorps cellular tumor antigen p53, anticorps transformation related protein 53, anticorps tumor protein p53 L homeolog, anticorps TP53, anticorps CpipJ_CPIJ002758, anticorps Tp53, anticorps tp53, anticorps Trp53, anticorps tp53.L

OMIM

191170

Pathways

Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg