HRAS anticorps (C-Term)
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- Antigène Voir toutes HRAS Anticorps
- HRAS (HRas proto-oncogene, GTPase (HRAS))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HRAS est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- N-RAS antibody is predicted to not cross-react with H-RAS
- Purification
- N-RAS Antibody is affinity chromatography purified via peptide column.
- Immunogène
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N-RAS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human N-RAS.
The immunogen is located within the last 50 amino acids of N-RAS. - Isotype
- IgG
- Top Product
- Discover our top product HRAS Anticorps primaire
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- Indications d'application
- N-RAS antibody can be used for detection of N-RAS by Western blot at 1 and 2 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- N-RAS Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- N-RAS antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- HRAS (HRas proto-oncogene, GTPase (HRAS))
- Autre désignation
- N-RAS (HRAS Produits)
- Synonymes
- anticorps C-BAS/HAS, anticorps C-H-RAS, anticorps C-HA-RAS1, anticorps CTLO, anticorps H-RASIDX, anticorps HAMSV, anticorps HRAS1, anticorps K-RAS, anticorps N-RAS, anticorps RASH1, anticorps hras, anticorps zgc:110250, anticorps HRAS, anticorps H-RAS, anticorps c-H-ras, anticorps H-Ras, anticorps K-Ras, anticorps hras1, anticorps rash1, anticorps ras, anticorps N-Ras, anticorps c-bas/has, anticorps H-ras, anticorps Ha-ras, anticorps Harvey-ras, anticorps Hras-1, anticorps Kras2, anticorps c-Ha-ras, anticorps c-rasHa, anticorps hrasl, anticorps zgc:110734, anticorps HRas proto-oncogene, GTPase, anticorps v-Ha-ras Harvey rat sarcoma viral oncogene homolog a, anticorps neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene, anticorps Harvey rat sarcoma viral oncogene homolog L homeolog, anticorps Harvey rat sarcoma viral oncogene homolog, anticorps Harvey rat sarcoma virus oncogene, anticorps NRAS proto-oncogene, GTPase, anticorps -Ha-ras Harvey rat sarcoma viral oncogene homolog b, anticorps HRAS, anticorps hrasa, anticorps LOC733587, anticorps Hras, anticorps hras.L, anticorps hras, anticorps NRAS, anticorps hrasb
- Sujet
- N-RAS Antibody: Activating mutations and overexpression of classical Ras subfamily members (N-RAS, H-RAS, and K-RAS) have been widely investigated as key events in the development of human cancers. The N-RAS protein shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. N-RAS, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
- Poids moléculaire
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Predicted: 22 kDa
Observed: 22 kDa - ID gène
- 4893
- NCBI Accession
- NP_002515
- UniProt
- P01111
- Pathways
- Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
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