BAK1 anticorps

N° du produit ABIN6291814

Détail du produit anti-BAK1 anticorps

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: A synthetic peptide of human BAK1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IHC 1:50 - 1:100

Commentaires:

Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur BAK1

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Autre désignation: BAK1 (BAK1 Produits)

Synonymes: anticorps BAK, anticorps BAK-LIKE, anticorps BCL2L7, anticorps CDN1, anticorps Bak, anticorps N-BAK1, anticorps N-Bak, anticorps Bak1, anticorps bak, anticorps bak1, anticorps BCL2 antagonist/killer 1, anticorps BCL2-antagonist/killer 1, anticorps BCL2 antagonist/killer 1 L homeolog, anticorps BAK1, anticorps Bak1, anticorps bak1.L

Sujet: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti-or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Poids moléculaire: 23.409 kDa

ID gène: 578

UniProt: Q16611

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response