GRB2 anticorps

N° du produit ABIN645847

Détail du produit anti-GRB2 anticorps

Antigène: GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Chèvre

Conjugué: Cet anticorp GRB2 est non-conjugé

Application: Veuillez nous consulter SVP

Specificité: The Goat Anti-GRB2 antibody detects protein derived from human recombinant protein and Jurkat kysate at various concentrations.

Réactivité croisée: Humain, Souris, Rat (Rattus), Chien, Poisson zèbre (Danio rerio)

Attributs du produit: Goat Anti-GRB2

Immunogène: Peptide with sequence C-PRNYVTPVNRNV, from the C Terminus of the protein sequence according to NP_002077.1, NP_987102.1, was used as an immunogen.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Stock: -20 °C

Détails sur GRB2

Antigène: GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))

Autre désignation: GRB2 (GRB2 Produits)

Synonymes: anticorps GRB2, anticorps grb2, anticorps AA408164, anticorps Ash, anticorps ASH, anticorps EGFRBP-GRB2, anticorps Grb3-3, anticorps MST084, anticorps MSTP084, anticorps NCKAP2, anticorps wu:fb18e12, anticorps wu:fb34e06, anticorps zgc:73077, anticorps growth factor receptor bound protein 2, anticorps growth factor receptor-bound protein 2, anticorps growth factor receptor-bound protein 2b, anticorps GRB2, anticorps grb2, anticorps Grb2, anticorps grb2b

Sujet: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_002077

Pathways: Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation