PRKAR2A anticorps

N° du produit ABIN7251907

Détail du produit anti-PRKAR2A anticorps

Antigène: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAR2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PRKAR2A

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:35-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKAR2A

Antigène: PRKAR2A (Protein Kinase, CAMP-Dependent, Regulatory, Type II, alpha (PRKAR2A))

Autre désignation: PRKAR2A (PRKAR2A Produits)

Synonymes: anticorps PKR2, anticorps PRKAR2, anticorps prkar2a, anticorps zgc:85886, anticorps PRKAR2A, anticorps 1110061A24Rik, anticorps AI317181, anticorps AI836829, anticorps RII(alpha), anticorps protein kinase cAMP-dependent type II regulatory subunit alpha, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, B, anticorps protein kinase, cAMP-dependent, regulatory, type II, alpha, anticorps protein kinase, cAMP dependent regulatory, type II alpha, anticorps protein kinase cAMP-dependent type 2 regulatory subunit alpha, anticorps PRKAR2A, anticorps prkar2ab, anticorps Prkar2a

Sujet: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 46 kDa

UniProt: P13861

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2