GSK3 beta anticorps (C-Term)

N° du produit ABIN7529527

Détail du produit anti-GSK3 beta anticorps

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSK3 beta est non-conjugé

Application: Western Blotting (WB)

Fonction: GSK3β Rabbit pAb

Séquence: PWTKVFRPRT PPEAIALCSR LLEYTPTARL TPLEACAHSF FDELRDPNVK LPNGRDTPAL FNFTTQELSS NPPLATILIP PHARIQAAAS TPTNATAASD ANTGDRGQTN NAASASASNS T

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GSK3beta (NP_001139628.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSK3 beta

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Autre désignation: GSK3B (GSK3b Produits)

Synonymes: anticorps GSK3, anticorps GSK-3, anticorps C86142, anticorps GSK-3beta, anticorps 7330414F15Rik, anticorps 8430431H08Rik, anticorps GSK3beta, anticorps fk80d11, anticorps GSK-3[b], anticorps wu:fb68h05, anticorps wu:fk80d11, anticorps gsk-3, anticorps gsk3, anticorps gsk3-beta, anticorps gsk3beta, anticorps xgsk-3, anticorps glycogen synthase kinase 3 beta, anticorps glycogen synthase kinase 3 beta L homeolog, anticorps GSK3B, anticorps Gsk3b, anticorps gsk3b, anticorps gsk3b.L

Sujet: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GSK3B,gsk-3β,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Regulation of eIF2,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centrosome,G1/S Checkpoint,Cell Adhesion,Microtubules,Hedgehog Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Carbohydrate metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Other Neurological disorders,Stem Cells,Cardiovascular,Heart,Hypertrophy,Akt downstream targets,GSK3B

Poids moléculaire: 46kDa/48kDa

ID gène: 2932

UniProt: P49841

Pathways: Signalisation WNT, Signalisation Hedgehog, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, L'effet Warburg