NLRP1 anticorps (AA 301-400) (Alexa Fluor 350)

N° du produit ABIN886487

Détail du produit anti-NLRP1 anticorps (Alexa Fluor 350)

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Épitope: AA 301-400

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP1 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CARD7/NALP1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NLRP1

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Autre désignation: CARD7 (NLRP1 Produits)

Synonymes: anticorps CARD7, anticorps CIDED, anticorps CLR17.1, anticorps DEFCAP, anticorps DEFCAP-L/S, anticorps NAC, anticorps NALP1, anticorps PP1044, anticorps SLEV1, anticorps VAMAS1, anticorps NLR family pyrin domain containing 1, anticorps NLRP1, anticorps Nlrp1

Sujet:

Synonyms: LRR and PYD domains-containing protein 1, CARD 7, CARD7, Caspase recruitment domain protein 7, Caspase recruitment domain-containing protein 7, CLR17.1, Death effector filament forming Ced 4 like apoptosis protein, Death effector filament-forming ced-4-like apoptosis protein, DEFCAP, DEFCAP L/S, NAC alpha/beta/gamma/delta, NAC, NACHT, NACHT leucine rich repeat and PYD containing 1, NACHT leucine rich repeat and PYD pyrin domain containing 1, NACHT leucine rich repeat and pyrin domain containing 1, NACHT LRR and PYD containing protein 1, NALP 1, NALP1, NALP1_HUMAN, NLR family pyrin domain containing 1, NLRP 1, NLRP1, NLRP1 protein, Nucleotide binding domain and caspase recruitment domain, Nucleotide binding oligomerization domain leucine rich repeat and pyrin domain containing 1, Nucleotide-binding domain and caspase recruitment domain, PP 1044, PP1044.

Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].

ID gène: 22861

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome