PIK3CA Protein (His tag)

N° du produit ABIN7319748

Détail du produit

Antigène: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PIK3CA protéine est marqué à la His tag.

Fonction: Recombinant Human PIK3CA Protein (His Tag)

Séquence: Met1-Pro200

Attributs du produit: A DNA sequence encoding the Human PIK3CA (P42336-1) (Met1-Pro200) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >90 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Autre désignation: PIK3CA (PIK3CA Produits)

Synonymes: CLOVE Protein, CWS5 Protein, MCAP Protein, MCM Protein, MCMTC Protein, PI3K Protein, p110-alpha Protein, C-P3K Protein, PI3-kinase Protein, PI3K-alpha Protein, pi3-k Protein, pi3k Protein, AA414921 Protein, C530050K14 Protein, p50alpha Protein, p55alpha Protein, p85alpha Protein, 6330412C24Rik Protein, caPI3K Protein, p110 Protein, p110alpha Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Protein, Phosphoinositide-3-kinase, catalytic, alpha polypeptide Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha Protein, phosphoinositide-3-kinase regulatory subunit 1 Protein, PIK3CA Protein, GL50803_14855 Protein, pik3ca Protein, Pik3ca Protein, Pik3r1 Protein

Sujet:

Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

Synonym: 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,5-bisphosphate 3-kinase catalytic subunit alpha isoform, caPI3K,CLOVE,CWS5,MCAP,MCM,MCMTC,MGC142161,MGC142163,p110 alpha,p110alpha,Phosphatidylinositol 3 kinase catalytic alpha polypeptide,Phosphatidylinositol 3 kinase catalytic 110 KD alpha,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform,Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha,Phosphatidylinositol-4,Phosphoinositide 3 kinase catalytic alpha polypeptide,PI3 kinase p110 subunit alpha,PI3-kinase subunit alpha,PI3K,PI3K-alpha,PI3KC A,PIK3C A,Pik3ca,PK3CA,PK3CA,PtdIns 3 kinase p110,PtdIns-3-kinase subunit alpha,PtdIns-3-kinase subunit p110-alpha,Serine/threonine protein kinase PIK3CA

Poids moléculaire: 23.1 kDa

Pathways: Signalisation PI3K-Akt, Signalisation RTK, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling