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SNCA Protéine

SNCA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
N° du produit ABIN934870
  • Antigène Voir toutes SNCA Protéines
    SNCA (Synuclein, alpha (SNCA))
    Type de proteíne
    Recombinant
    Origine
    • 25
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 25
    • 13
    • 3
    • 2
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Séquence
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
    Attributs du produit
    Purified recombinant Human alpha Synuclein protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
    Pureté
    > 95 % pure
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    < 1.0 EU per µg of protein (determined by LAL method)
    Top Product
    Discover our top product SNCA Protéine
  • Indications d'application
    Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in sterile distilled water at a concentration of 1 mg/mL or less.
    Concentration
    1 mg/mL
    Buffer
    Lyophilized from a 0.2 µm filtered in 20 mM Tris-HCl buffer, pH 7.5, containing 100 mM NaCl, and 0 mM MgCl2.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    RT/-20 °C
    Stockage commentaire
    The product is shipped at ambient temperature. Upon receipt, store it immediately at 4 °C in the short term (1 month). For long term storage, aliquot and store at -20 °C or -70 °C.
  • Antigène
    SNCA (Synuclein, alpha (SNCA))
    Autre désignation
    alpha Synuclein (SNCA Produits)
    Synonymes
    snca Protein, MGC64356 Protein, LOC619283 Protein, NACP Protein, alphaSYN Protein, PARK1 Protein, PARK4 Protein, PD1 Protein, synuclein alpha L homeolog Protein, alpha-synuclein Protein, synuclein alpha Protein, synuclein, alpha Protein, snca.L Protein, LOC619283 Protein, SNCA Protein, Snca Protein
    Sujet
    Alpha-Synuclein, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140).
    Alternative Names: alphaSYN protein, SNCA protein, Non-A beta component of AD amyloid protein, PARK1 protein, , Non-A4 component of amyloid precursor protein, Synuclein alpha protein, MGC64356 protein, PARK 4 protein, Non-A-beta component of alzheimers disease amyloid protein, MGC127560 protein, Non A beta component of AD amyloid protein, Parkinson disease familial 1 protein, Non A4 component of amyloid precursor protein, alpha-Synuclein protein, MGC110988 protein, NACP protein, Alpha-synuclein isoform NACP140 protein, PD1 protein, precursor of PARK 1 protein, MGC105443 protein, Alpha synuclein protein, PD 1 protein, PARK4 protein
    Poids moléculaire
    14.4 kDa (140 AA)
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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