anti-Souris ATM anticorps pour Chromatin Immunoprecipitation

Recommended ATM Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Ataxia Telangiectasia Mutated (ATM) Anticorps
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ATM serine/threonine kinase L homeolog
  • ATM serine/threonine kinase
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • serine/threonine-protein kinase ATM
  • tefu
  • atm.L
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • LOC5565620
  • MGYG_07634
  • PGTG_14279
  • Atm
Épitope
full length
89
40
17
16
15
15
8
8
6
6
6
6
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Singe, Souris, Rat (Rattus)
357
157
77
26
8
1
1
1
1
Hôte
Souris
231
99
17
9
3
Clonalité
Monoclonal
Conjugué
Cet anticorp ATM est non-conjugé
12
11
10
9
8
6
5
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
221
125
110
86
85
69
58
43
27
22
13
6
4
4
2
2
1
1
1
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N° du produit ABIN151775
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1721458 ChIP ICC FACS IF IP IHC ELISA WB Mouse IgG1 kappa AA 2577-3056, full length Connectez-vous pour afficher 2C1 0

General

Antigène Ataxia Telangiectasia Mutated (ATM) Anticorps
Épitope full length
(89), (40), (17), (16), (15), (15), (8), (8), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Singe, Souris, Rat (Rattus)
(357), (157), (77), (26), (8), (1), (1), (1), (1)
Hôte Souris
(231), (99), (17), (9), (3)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp ATM est non-conjugé
(12), (11), (10), (9), (8), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(221), (125), (110), (86), (85), (69), (58), (43), (27), (22), (13), (6), (4), (4), (2), (2), (1), (1), (1)
Pubmed 114 références disponible
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Détail du produit anti-ATM anticorps

Détail du antigène ATM Information d'application Stockage References for anti-ATM antibody (ABIN151775) Images
Specificité This antibody recognizes full-length ATM, a 350- kDa nuclear phosphoprotein.
Purification Protein G purified
Immunogène Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Clone 2C1
Isotype IgG1

Détail du antigène ATM

Détail du produit anti-ATM anticorps Information d'application Stockage References for anti-ATM antibody (ABIN151775) Images Haut de la page
Antigène
Autre désignation ATM (ATM Antibody Extrait)
Sujet Gene Symbol: ATM
Poids moléculaire Theoretical MW: 370 kDa
ID gène 472
UniProt Q13315
Pathways Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Information d'application

Détail du produit anti-ATM anticorps Détail du antigène ATM Stockage References for anti-ATM antibody (ABIN151775) Images Haut de la page
Indications d'application Western Blot 1:500-1:3000, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry, ELISA 1:100 - 1:2000, Immunohistochemistry 10 - 1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1-10 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLIHC-R. ICC/IF usage reported in scientifc literature (Harry Scherthan, et.al., 2000 and Yiyoung Liu, et.al., 2006). ELISA usage reported in scientific literature. WB: Predicted molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Stockage

Détail du produit anti-ATM anticorps Détail du antigène ATM Information d'application References for anti-ATM antibody (ABIN151775) Images Haut de la page
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS ( pH 7.4)
Buffer contains: No Preservative
Agent conservateur Without preservative
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock -80 °C,-20 °C
Stockage commentaire Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

References for anti-ATM antibody (ABIN151775)

Détail du produit anti-ATM anticorps Détail du antigène ATM Information d'application Stockage Images Haut de la page
Produit citée dans:

Simões, Martins, Ferreira: "Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus." dans: Virus research, Vol. 210, pp. 1-7, 2015

Park, Kong, Kim, Lee, Park: "Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest." dans: American journal of cancer research, Vol. 5, Issue 7, pp. 2127-38, 2015 Détails: Western Blotting

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." dans: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, 2015 (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Vermezovic, Adamowicz, Santarpia, Rustighi, Forcato, Lucano, Massimiliano, Costanzo, Bicciato, Del Sal, dAdda di Fagagna: "Notch is a direct negative regulator of the DNA-damage response." dans: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 417-24, 2015 (Échantillon (espèces): Human). Détails: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Muraki, Han, Miller, Murnane: "Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks." dans: Nucleic acids research, Vol. 43, Issue 16, pp. 7911-30, 2015 (Échantillon (espèces): Human). Détails: Western Blotting

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." dans: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (Échantillon (espèces): Human). Détails: Western Blotting

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." dans: Nature communications, Vol. 4, pp. 2993, 2013 (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Murad, Cullen, McKenzie, Ryan, Thorburn, Gueven, Kobayashi, Birrell, Yang, Dörk, Becherel, Grattan-Smith, Lavin: "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia." dans: Mitochondrion, Vol. 13, Issue 3, pp. 235-45, 2013 (Échantillon (espèces): Human). Détails: Western Blotting

Simões, Martins, Ferreira: "Host DNA damage response facilitates African swine fever virus infection." dans: Veterinary microbiology, Vol. 165, Issue 1-2, pp. 140-7, 2013

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." dans: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." dans: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 Détails: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." dans: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (Échantillon (espèces): Human). Détails: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." dans: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." dans: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." dans: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." dans: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Baritaud, Cabon, Delavallée, Galán-Malo, Gilles, Brunelle-Navas, Susin: "AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation." dans: Cell death & disease, Vol. 3, pp. e390, 2012 Détails: Western Blotting

Shi, Felley-Bosco, Marti, Stahel: "Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45354, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, 2012 (Échantillon (espèces): Human). Détails: Western Blotting

Images

Détail du produit anti-ATM anticorps Détail du antigène ATM Information d'application Stockage References for anti-ATM antibody (ABIN151775) Haut de la page
Supplier Images
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug U87-MG whole cell lysate/ext...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug NT2D1 whole cell lysate/extr...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - analysis of ATM in U2OS sarcoma cells...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Testis (formal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Kidney (formal...