Src anticorps (AA 2-368)
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- Antigène Voir toutes Src Anticorps
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Épitope
- AA 2-368
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Src est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Proto-oncogene tyrosine-protein kinase Src(SRC) detection. Tested with WB, IHC-P in Human.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Proto-oncogene tyrosine-protein kinase Src(SRC) detection. Tested with WB, IHC-P in Human.
Gene Name: SRC proto-oncogene, non-receptor tyrosine kinase
Protein Name: Proto-oncogene tyrosine-protein kinase Src - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human Src recombinant protein (Position: G2-D368). Human Src shares 97% and 99% amino acid (aa) sequence identity with mouse and rat Src, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product Src Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Src is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/?-catenin pathway." dans: Oncotarget, Vol. 6, Issue 5, pp. 3123-35, (2015) (PubMed).
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Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/?-catenin pathway." dans: Oncotarget, Vol. 6, Issue 5, pp. 3123-35, (2015) (PubMed).
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- Antigène
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- Autre désignation
- SRC (Src Produits)
- Synonymes
- anticorps AW259666, anticorps pp60c-src, anticorps C-src1, anticorps CG7524, anticorps D-Src64B, anticorps D-src, anticorps DSRC64, anticorps DSrc, anticorps DSrc64, anticorps DSrc64B, anticorps Dm SRC1, anticorps DmHD-358, anticorps Dmel\CG7524, anticorps Dsrc, anticorps Dsrc64, anticorps Dsrc64B, anticorps HD-358, anticorps MRE5, anticorps SRC 64B, anticorps Src, anticorps Src1, anticorps Src64, anticorps c-src, anticorps dSrc, anticorps dsrc, anticorps src, anticorps src1, anticorps src64, anticorps src64B, anticorps src64b, anticorps ASV, anticorps SRC1, anticorps c-SRC, anticorps p60-Src, anticorps c-Src, anticorps PP60C-SCR, anticorps SDR, anticorps SRC proto-oncogene, non-receptor tyrosine kinase, anticorps uncharacterized LOC5574802, anticorps proto-oncogene tyrosine-protein kinase src, anticorps Rous sarcoma oncogene, anticorps Src oncogene at 64B, anticorps SRC, anticorps LOC5574802, anticorps CpipJ_CPIJ010659, anticorps Src, anticorps Src64B
- Classe de substances
- Viral Protein
- Sujet
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Sarcoma (Scr) is a proto-oncogenic tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus. belongs to a family of non-receptor tyrosine kinases called Src family kinases. The human SRC protooncogene was assigned to chromosome 20. Its gene is mapped to 20q12-q13. The discovery of Src family proteins has been instrumental to the modern understanding of cancer as a disease where normally healthy cellular signalling has gone awry. This proto-oncogene may play a role in the regulation of embryonic development and cell growth.
Synonyms: ASV antibody|Avian sarcoma virus antibody|c SRC antibody|CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody|cSrc antibody|EC 2.7.10.2 antibody|Neuronal CSRC tyrosine specific protein kinase antibody|Neuronal SRC antibody|Oncogene SRC antibody|OTTHUMP00000030931 antibody|OTTHUMP00000174476 antibody|OTTHUMP00000174477 antibody|p60 Src antibody|p60-Src antibody|p60Src antibody|pp60c src antibody|pp60c-src antibody|pp60csrc antibody|Proto oncogene tyrosine protein kinase Src antibody|Proto-oncogene c-Src antibody|Proto-oncogene tyrosine-protein kinase Src antibody|Protooncogene SRC antibody|protooncogene SRC Rous sarcoma antibody|Src antibody|SRC Oncogene antibody|SRC_HUMAN antibody|SRC1 antibody|Tyrosine kinase pp60c src antibody|Tyrosine protein kinase SRC 1 antibody|Tyrosine protein kinase SRC1 antibody|v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody|V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody|v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody|vsrc avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody - ID gène
- 6714
- UniProt
- P12931
- Pathways
- Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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