c-MET anticorps (pTyr1349, pTyr1356)

N° du produit ABIN550491

Détail du produit anti-c-MET anticorps

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Épitope: pTyr1349, pTyr1356

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Fonction: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MET.

Specificité: This antibody is specific to human c-Met protein phosphorylated at Y1349 and Y1356.

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Antibody Reactive Against Synthetic Peptide.

Immunogène: Synthetic phosphopeptide corresponding to residues surrounding Y1349/Y1356 of human MET.

Information d'application

Indications d'application: ELISA (1:450000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-c-MET (ABIN550491)

Pavone, Cattaneo, Rea, De Pasquale, Spina, Sauchelli, Mastellone, Ammendola: "Intracellular signaling cascades triggered by the NK1 fragment of hepatocyte growth factor in human prostate epithelial cell line PNT1A." dans: Cellular signalling, Vol. 23, Issue 12, pp. 1961-71, (2011) (PubMed).

Birchmeier, Birchmeier, Gherardi, Vande Woude: "Met, metastasis, motility and more." dans: Nature reviews. Molecular cell biology, Vol. 4, Issue 12, pp. 915-25, (2003) (PubMed).

Fan, Ma, Gao, Yuan, Meng, Goldberg, Rosen: "The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair." dans: Molecular and cellular biology, Vol. 21, Issue 15, pp. 4968-84, (2001) (PubMed).

Longati, Comoglio, Bardelli: "Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene." dans: Current drug targets, Vol. 2, Issue 1, pp. 41-55, (2001) (PubMed).

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: HGF receptor (MET Produits)

Synonymes: anticorps AUTS9, anticorps HGFR, anticorps RCCP2, anticorps c-Met, anticorps AI838057, anticorps HGF, anticorps Par4, anticorps Hgfr, anticorps c-met, anticorps MET, anticorps C-MET, anticorps met, anticorps met-A, anticorps MET proto-oncogene, receptor tyrosine kinase, anticorps met proto-oncogene, anticorps MET proto-oncogene, receptor tyrosine kinase L homeolog, anticorps MET, anticorps Met, anticorps met.L

ID gène: 4233

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor