ADAM17 anticorps (C-Term)

N° du produit ABIN5516417

Détail du produit anti-ADAM17 anticorps

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM17 est non-conjugé

Application: Western Blotting (WB)

Séquence: DGFEKDPFPN SSTAAKSFED LTDHPVTRSE KAASFKLQRQ NRVDSKETEC

Attributs du produit: This is a rabbit polyclonal antibody against ADAM17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADAM17

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ADAM17

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Autre désignation: ADAM17 (ADAM17 Produits)

Synonymes: anticorps ADAM18, anticorps CD156B, anticorps CSVP, anticorps NISBD, anticorps TACE, anticorps CD156b, anticorps Tace, anticorps adam17, anticorps si:dkey-81b15.2, anticorps adam18, anticorps cd156b, anticorps csvp, anticorps tace, anticorps fc20b01, anticorps wu:fc20b01, anticorps zgc:63886, anticorps ADAM metallopeptidase domain 17, anticorps a disintegrin and metallopeptidase domain 17, anticorps ADAM metallopeptidase domain 17b, anticorps ADAM metallopeptidase domain 17 L homeolog, anticorps ADAM metallopeptidase domain 17a, anticorps ADAM17, anticorps Adam17, anticorps adam17b, anticorps adam17.L, anticorps adam17a

Sujet: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

Alias Symbols: ADAM17, CSVP, TACE,

Protein Interaction Partner: UBC, EED, PXN, TNFRSF1B, TNFRSF1A, PDIA3, FBXO6, SH3D19, TGFA, MAD2L2, PTPN3, TNFSF11, FHL2, MAD2L1, DLG1, ERBB4, TNF, NOTCH1, TIMP3, MAPK1,

Protein Size: 824

ID gène: 6868

NCBI Accession: NP_003174

UniProt: P78536

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus