PRKAR2B anticorps

N° du produit ABIN6944655

Détail du produit anti-PRKAR2B anticorps

Antigène: PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAR2B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: N terminal human PRKAR2B

Clone: 5G1

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PRKAR2B

Antigène: PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B))

Autre désignation: PRKAR2B (PRKAR2B Produits)

Synonymes: anticorps MGC83177, anticorps PRKAR2B, anticorps AI451071, anticorps AW061005, anticorps PKARIIbeta, anticorps Pkarb2, anticorps RII(beta), anticorps RATDNA, anticorps PRKAR2, anticorps RII-BETA, anticorps protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog, anticorps protein kinase cAMP-dependent type II regulatory subunit beta, anticorps protein kinase, cAMP-dependent, regulatory, type II, beta, anticorps protein kinase, cAMP dependent regulatory, type II beta, anticorps protein kinase cAMP-dependent type 2 regulatory subunit beta, anticorps prkar2b.S, anticorps PRKAR2B, anticorps prkar2b, anticorps Prkar2b

Sujet:

Synonyms: cAMP-dependent protein kinase type II-beta regulatory subunit, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, PRKAR2, RII-BETA

Background: PRKAR2B is a regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol.

ID gène: 5577

UniProt: P31323

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2