PKC zeta anticorps
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- Antigène Voir toutes PKC zeta (PRKCZ) Anticorps
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKC zeta est non-conjugé
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Application
- Western Blotting (WB)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human PRKCZ (NP_002735.3).
- Isotype
- IgG
- Top Product
- Discover our top product PRKCZ Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
- Autre désignation
- PRKCZ (PRKCZ Produits)
- Synonymes
- anticorps TPKC, anticorps PKCzeta, anticorps prkcz-A, anticorps pkc-zeta, anticorps PRKCZ, anticorps pkc2, anticorps PKC-ZETA, anticorps PKC2, anticorps AI098070, anticorps C80388, anticorps Pkcz, anticorps R74924, anticorps aPKCzeta, anticorps zetaPKC, anticorps 14-3-3-zetaisoform, anticorps r14-3-3, anticorps pkcz, anticorps si:ch211-150o23.4, anticorps protein kinase C zeta L homeolog, anticorps protein kinase C zeta, anticorps protein kinase C, zeta, anticorps prkcz.L, anticorps PRKCZ, anticorps prkcz, anticorps Prkcz
- Sujet
- Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Poids moléculaire
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Observed_MW: 78 kDa
Calculated_MW: 46 kDa/56 kDa/67 kDa
- ID gène
- 5590
- UniProt
- Q05513
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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