ATF4 anticorps (pSer245)
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- Antigène Voir toutes ATF4 Anticorps
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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Épitope
- pSer245
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATF4 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogène
- Peptide sequence around phosphorylation site of serine 245 (N-R-S(p)-L-P) derived from Human ATF4.
- Isotype
- IgG
- Top Product
- Discover our top product ATF4 Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
- Autre désignation
- ATF4 (ATF4 Produits)
- Synonymes
- anticorps CREB-2, anticorps CREB2, anticorps TAXREB67, anticorps TXREB, anticorps ATF4, anticorps atf-4, anticorps creb-2, anticorps creb2, anticorps taxreb67, anticorps txreb, anticorps atf4, anticorps wu:fj01c08, anticorps wu:fk30b04, anticorps zgc:85951, anticorps sb:eu681, anticorps wu:fb08f07, anticorps zgc:171702, anticorps Atf-4, anticorps C/ATF, anticorps ATF4-I, anticorps atf4-a, anticorps atf4-b, anticorps atf4-ii, anticorps activating transcription factor 4, anticorps activating transcription factor 4 L homeolog, anticorps activating transcription factor 4a, anticorps activating transcription factor 4b, anticorps activating transcription factor 4 S homeolog, anticorps ATF4, anticorps atf4, anticorps Atf4, anticorps atf4.L, anticorps atf4a, anticorps atf4b, anticorps atf4.S
- Sujet
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Background: ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA bindingprotein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Yang X, et al. (2004). Cell.117(3): 387-398.Aliases: Activating transcription factor 4 antibody, ATF 4 antibody, ATF4 antibody, ATF4 protein antibody, ATF4_HUMAN antibody, cAMP-dependent transcription factor ATF-4 antibody, cAMP-responsive element-binding protein 2 antibody, CREB 2 antibody, CREB-2 antibody, CREB2 antibody, Cyclic AMP dependent transcription factor ATF 4 antibody, Cyclic AMP response element binding protein 2 antibody, Cyclic AMP-dependent transcription factor ATF-4 antibody, Cyclic AMP-responsive element-binding protein 2 antibody, DNA binding protein TAXREB67 antibody, DNA-binding protein TAXREB67 antibody, Tax Responsive Enhancer Element B67 antibody, Tax-responsive enhancer element-binding protein 67 antibody, TaxREB67 antibody, TXREB antibody
- UniProt
- P18848
- Pathways
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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