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Phospholipase C gamma 1 anticorps (pSer1248)
PLCG1
Reactivité: Humain
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7269347
Détail du produit anti-Phospholipase C gamma 1 anticorps
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Antigène
Voir toutes Phospholipase C gamma 1 (PLCG1) Anticorps
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Épitope
Tous les épitopes à travers Phospholipase C gamma 1 Anticorps.
pSer1248
Reactivité
Toutes les réactivités sur Phospholipase C gamma 1 Anticorps
Humain
Hôte
Toutes les hôtes sur Phospholipase C gamma 1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur Phospholipase C gamma 1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Phospholipase C gamma 1 Anticorps
Cet anticorp Phospholipase C gamma 1 est non-conjugé
Application
Tous les applications à travers Phospholipase C gamma 1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Fonction
Phospho-PLC gamma 1 (PLCG1)-S1248 Rabbit pAb
Séquence
REGSF
Réactivité croisée
Humain, Souris, Rat
Attributs du produit
Phosphorylated Antibodies
Purification
Affinity purification
Immunogène
A synthetic phosphorylated peptide around S1248 of human PLC gamma 1 (PLCG1) (NP_002651.2).
Isotype
IgG
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Discover our top product PLCG1 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
WB,1:500 - 1:2000,IHC,1:10 - 1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur Phospholipase C gamma 1
(cache)
Antigène
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Autre désignation
PLCG1 (PLCG1 Produits )
Synonymes
anticorps NCKAP3, anticorps PLC-II, anticorps PLC1, anticorps PLC148, anticorps PLCgamma1, anticorps plc1, anticorps nckap3, anticorps plc-ii, anticorps plc148, anticorps plcgamma1, anticorps PPLCA, anticorps AI894140, anticorps Cded, anticorps Plc-1, anticorps Plc-gamma1, anticorps Plcg-1, anticorps fj46f04, anticorps wu:fj46f04, anticorps wu:fj57a05, anticorps phospholipase C gamma 1, anticorps phospholipase C gamma 1 L homeolog, anticorps 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, anticorps phospholipase C, gamma 1, anticorps PLCG1, anticorps plcg1.L, anticorps LOC100633163, anticorps Plcg1, anticorps plcg1
Sujet
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.,PLCG1,NCKAP3,PLC-II,PLC1,PLC148,PLCgamma1,Cancer,Signal Transduction,Phospholipase Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,Protein phosphorylation,PLCG1
Poids moléculaire
148kDa
ID gène
5335
UniProt
P19174
Pathways
Signalisation RTK , Signalisation WNT , TCR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Thyroid Hormone Synthesis , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , Skeletal Muscle Fiber Development , G-protein mediated Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Interaction of EGFR with phospholipase C-gamma , VEGFR1 Specific Signals , VEGF Signaling
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