Phospholipase C gamma 1 anticorps (pTyr771) (Alexa Fluor 488)

N° du produit ABIN880158

Détail du produit anti-Phospholipase C gamma 1 anticorps (Alexa Fluor 488)

Antigène: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Épitope: pTyr771

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C gamma 1 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr771

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Phospholipase C gamma 1

Antigène: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Autre désignation: PLC gamma 1 (PLCG1 Produits)

Synonymes: anticorps NCKAP3, anticorps PLC-II, anticorps PLC1, anticorps PLC148, anticorps PLCgamma1, anticorps plc1, anticorps nckap3, anticorps plc-ii, anticorps plc148, anticorps plcgamma1, anticorps PPLCA, anticorps AI894140, anticorps Cded, anticorps Plc-1, anticorps Plc-gamma1, anticorps Plcg-1, anticorps fj46f04, anticorps wu:fj46f04, anticorps wu:fj57a05, anticorps phospholipase C gamma 1, anticorps phospholipase C gamma 1 L homeolog, anticorps 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, anticorps phospholipase C, gamma 1, anticorps PLCG1, anticorps plcg1.L, anticorps LOC100633163, anticorps Plcg1, anticorps plcg1

Sujet:

Synonyms: PLC 1, PLC 148, PLC gamma 1, PLC II, PLC1, PLC148, PLCG 1, PLCG1, PLCgamma1, PLCII, triphosphoinositide phosphodiesterase, 1 phosphatidyl D myo inositol 4 5 bisphosphate, 1 phosphatidylinositol 4 5 bisphosphate, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, phosphodiesterase gamma 1, phosphoinositidase C, phosphoinositide phospholipase C, Phospholipase C 148, phospholipase C gamma 1 formerly subtype 148, Phospholipase C gamma 1, phospholipase C-148, PLCG1_HUMAN.

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

ID gène: 5335

Pathways: Signalisation RTK, Signalisation WNT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling