Parkinson's disease

Parkinson's disease is one of the most well known neurodegenerative diseases. It is a chronic, progressive neurodegenerative disease characterized by both motor and nonmotor features. The disease has a significant clinical impact on patients, families, and caregivers through its progressive degenerative effects on mobility and muscle control.(1) An estimated 7 to 10 million people worldwide suffer from Parkinson's disease. antibodies-online offers a hand-picked number of antibodies, ELISA kits, recombinant proteins, as well as other tools for Parkinson's research.

Here you will find a list of important antibodies, reagents, kits, and other tools you need for your research in the field of Parkinson's disease, as well as some more additional resources on the topic.

Important Targets in Parkinson's Research

The following targets are directly related to research on Parkinson's disease. Search Antibodies, Kits, Reagents and other products. Click on a gene to see the available products.

Autosomal recessive and X-linked genes involved in Parkinson’s disease(2)

Autosomal dominant genes involved in Parkinson’s disease(2)

alpha-Synuclein (SNCA) / PARK1

α-Synuclein is a presynaptic neuronal protein that is linked genetically and neuropathologically to Parkinson's disease (PD).(3) We offer a variety of reliable mono- and polyclonal SNCA antibodies.

Produit Reactivity Clonalité Application N° du produit Quantité Relevance ProductGrid: uniqueid
anti-SNCA anticorps (Synuclein, alpha) (pSer129) Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Primate, Rat (Rattus) Polyclonal WB ABIN2477391 0.1 mL element-ABIN2477391
anti-SNCA anticorps (Synuclein, alpha) Human Monoclonal IHC, ELISA, WB ABIN1724652 100 μL element-ABIN1724652
anti-SNCA anticorps (Synuclein, alpha) Human Polyclonal IF, WB ABIN6148190 100 μL element-ABIN6148190
anti-SNCA anticorps (Synuclein, alpha) Mammalian Monoclonal ELISA, IF, IHC, WB ABIN536927 100 μL element-ABIN536927

See all alpha-Synuclein Antibodies

LRRK2 / PARK8

As a promising target for neuroprotection strategies in PD, in vitro and in vivo models that accurately demonstrate LRRK2's function relevant to neurodegeneration will aide in the identification of molecules with the highest chance of success in the clinic.(4)

Produit Reactivity Clonalité Application N° du produit Quantité Relevance ProductGrid: uniqueid
anti-LRRK2 anticorps (Leucine-Rich Repeat Kinase 2) (AA 930-961) Human, Mouse (Murine) Polyclonal IF, ELISA, WB ABIN3031610 0.4 mL element-ABIN3031610
anti-LRRK2 anticorps (Leucine-Rich Repeat Kinase 2) (C-Term) Human, Mouse (Murine) Monoclonal ELISA, WB ABIN3031612 0.4 mL element-ABIN3031612
anti-LRRK2 anticorps (Leucine-Rich Repeat Kinase 2) (AA 878-909) Human, Mouse (Murine) Polyclonal IHC, ELISA, WB ABIN3031607 0.4 mL element-ABIN3031607
anti-LRRK2 anticorps (Leucine-Rich Repeat Kinase 2) (AA 931-962) Human Polyclonal IHC, ELISA, WB ABIN3028794 0.4 mL element-ABIN3028794

DJ-1 / PARK7

The DJ-1 gene is a causative gene for familial PD (park7) and also an oncogene. DJ-1 has various functions, including transcriptional regulation, antioxidative stress reaction, and chaperone, protease, and mitochondrial regulation.(5)

Produit Reactivity Clonalité Application N° du produit Quantité Relevance ProductGrid: uniqueid
anti-PARK7 anticorps (Parkinson Protein 7) Human Polyclonal ELISA, WB ABIN545411 400 μL element-ABIN545411
anti-PARK7 anticorps (Parkinson Protein 7) Human Monoclonal ELISA, WB ABIN532936 100 μL element-ABIN532936

See all DJ-1 Antibodies

Featured ELISA Kits

Here you will find a range of reliable ELISA kits with PubMed references for a number of PD related targets, which allow a quick and easy detection of proteins in biological samples. Click on the links to find more information.

Produit Reactivity Detection Method N° du produit Quantité Relevance ProductGrid: uniqueid
PARK2 Kit IQ-ELISA (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin)) Human qPCR
(Pre-coated)
ABIN6386150 96 tests element-ABIN6386150
PARK7 Kit IQ-ELISA (Parkinson Protein 7) Human qPCR
(Pre-coated)
ABIN6386133 96 tests element-ABIN6386133
SNCA Kit ELISA (Synuclein, alpha) Rat (Rattus) Colorimetric
(Pre-coated)
ABIN431993 96 tests element-ABIN431993
PARK7 Kit ELISA (Parkinson Protein 7) Mouse (Murine) Colorimetric
(Pre-coated)
ABIN819944 96 tests element-ABIN819944
SNCA Kit ELISA (Synuclein, alpha) Mouse (Murine) Colorimetric
(Pre-coated)
ABIN415770 96 tests element-ABIN415770
SNCA Kit ELISA (Synuclein, alpha) Human Colorimetric
(Pre-coated)
ABIN414578 96 tests element-ABIN414578

References

(1) DeMaagd G, Philip A. Parkinson's Disease and Its Management: Part 1: Disease Entity, Risk Factors, Pathophysiology, Clinical Presentation, and Diagnosis. P T. 2015 Aug;40(8):504-32. PMID: 26236139; PMCID: PMC4517533.

(2) Emamzadeh, F. N., & Surguchov, A. (2018). Parkinson's Disease: Biomarkers, Treatment, and Risk Factors. Frontiers in neuroscience, 12, 612. doi:10.3389/fnins.2018.00612

(3) Stefanis L. α-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med. 2012 Feb;2(2):a009399. doi: 10.1101/cshperspect.a009399. PMID: 22355802; PMCID: PMC3281589.

(4) Webber PJ, West AB. LRRK2 in Parkinson's disease: function in cells and neurodegeneration. FEBS J. 2009 Nov;276(22):6436-44. doi: 10.1111/j.1742-4658.2009.07342.x.

(5) Ariga H, Takahashi-Niki K, Kato I, Maita H, Niki T, Iguchi-Ariga SM. Neuroprotective function of DJ-1 in Parkinson's disease. Oxid Med Cell Longev. 2013;2013:683920. doi: 10.1155/2013/683920. Epub 2013 May 16. PMID: 23766857; PMCID: PMC3671546.