HRAS Protein (AA 1-186) (His tag)

N° du produit ABIN666969

Détail du produit

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Type de proteíne: Recombinant

Attributs du protein: AA 1-186

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HRAS protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: HRAS, 1-186aa, Human, His-tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Autre désignation: HRAS (HRAS Produits)

Synonymes: C-BAS/HAS Protein, C-H-RAS Protein, C-HA-RAS1 Protein, CTLO Protein, H-RASIDX Protein, HAMSV Protein, HRAS1 Protein, K-RAS Protein, N-RAS Protein, RASH1 Protein, hras Protein, zgc:110250 Protein, HRAS Protein, H-RAS Protein, c-H-ras Protein, H-Ras Protein, K-Ras Protein, hras1 Protein, rash1 Protein, ras Protein, N-Ras Protein, c-bas/has Protein, H-ras Protein, Ha-ras Protein, Harvey-ras Protein, Hras-1 Protein, Kras2 Protein, c-Ha-ras Protein, c-rasHa Protein, hrasl Protein, zgc:110734 Protein, HRas proto-oncogene, GTPase Protein, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a Protein, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene Protein, Harvey rat sarcoma viral oncogene homolog L homeolog Protein, Harvey rat sarcoma viral oncogene homolog Protein, Harvey rat sarcoma virus oncogene Protein, NRAS proto-oncogene, GTPase Protein, -Ha-ras Harvey rat sarcoma viral oncogene homolog b Protein, HRAS Protein, hrasa Protein, LOC733587 Protein, Hras Protein, hras.L Protein, hras Protein, NRAS Protein, hrasb Protein

Sujet: HRAS, also known as GTPase HRas, belongs to the Ras family which function in signal transduction pathways. This protein can bind GTP and GDP, and it has intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Defects in HRAS are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Recombinant human HRAS protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HMG14, GC104230, v-Ha-ras Harvey rat sarcoma viral oncogene homolog C BAS/HAS, c H ras, C HA RAS1, c has/bas p21 protein, c ras Ki 2 activated oncogene, CTLO, GTP and GDP binding peptide B, H Ras 1, H RASIDX, Ha Ras, Ha Ras1 proto oncoprotein, HAMSV, HRAS, HRAS1, K ras, N ras, p19 H RasIDX protein, p21ras, Ras family small GTP binding protein H Ras, RASH1, Transformation gene oncogene HAMSV, Transforming protein p21, v Ha ras Harvey rat sarcoma viral oncogene homolog, VH Ras, vHa RAS. NCBI no.: NP_001123914

Poids moléculaire: 22.0 kDa (194aa), confirmed by MALDI-TOF.

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling