GTPase NRas Protein (NRAS) (AA 1-186)

N° du produit ABIN667768

Détail du produit

Antigène: GTPase NRas (NRAS)

Type de proteíne: Recombinant

Attributs du protein: AA 1-186

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Attributs du produit: NRAS, 1-186aa, Human, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: GTPase NRas (NRAS)

Autre désignation: NRAS (NRAS Produits)

Synonymes: NRAS Protein, AV095280 Protein, N-ras Protein, ALPS4 Protein, NRAS1 Protein, NS6 Protein, N-RAS Protein, fj99a10 Protein, wu:fj99a10 Protein, zgc:100761 Protein, zras-b1 Protein, H-RAS Protein, HRAS Protein, GTPase NRas Protein, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog Protein, NRAS proto-oncogene, GTPase Protein, neuroblastoma ras oncogene Protein, neuroblastoma RAS viral oncogene homolog Protein, Tsp_01117 Protein, nras.L Protein, Nras Protein, NRAS Protein, nras Protein

Sujet: Neuroblastoma RAS viral (v-ras) oncogene homolog, also known as NRAS, is a member of the RAS gene family. NRAS is an oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Recombinant human NRAS was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GTPase NRas, HRAS1, ALPS4, N-ras, NRAS1, NS6, Neuroblastoma RAS viral (v-ras) oncogene homolog OTTMUSP00000023521, AV095280, N ras, N ras protein part 4, Neuroblastoma RAS viral (v ras) oncogene homolog, OTTHUMP00000013879, Transforming protein N Ras, v ras neuroblastoma RAS viral oncogene homolog. NCBI no.: NP_002515

Poids moléculaire: 20.8 kDa (186aa), confirmed by MALDI-TOF.

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling