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PTPN11 anticorps
PTPN11
Reactivité: Humain, Souris
WB
Hôte: Souris
Monoclonal
246CT9-8-2
unconjugated
Détail du produit anti-PTPN11 anticorps
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Antigène
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PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
Reactivité
Toutes les réactivités sur PTPN11 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur PTPN11 Anticorps
Souris
Clonalité
Toutes les clonalités sur PTPN11 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers PTPN11 Anticorps
Cet anticorp PTPN11 est non-conjugé
Application
Tous les applications à travers PTPN11 Anticorps.
Western Blotting (WB)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogène
This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein.
Clone
246CT9-8-2
Isotype
IgG1 kappa
Top Product
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Alternatives
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Information d'application
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Indications d'application
WB: 1:100. WB: 1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
PTPN11 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Date de péremption
6 months
Détails sur PTPN11
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Antigène
PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
Autre désignation
PTPN11 (PTPN11 Produits )
Synonymes
anticorps BPTP3, anticorps CFC, anticorps NS1, anticorps PTP-1D, anticorps PTP2C, anticorps SH-PTP2, anticorps SH-PTP3, anticorps SHP2, anticorps 2700084A17Rik, anticorps AW536184, anticorps PTP1D, anticorps SAP-2, anticorps SHP-2, anticorps Shp2, anticorps Syp, anticorps SYP, anticorps bptp3, anticorps cfc, anticorps ns1, anticorps ptp-2, anticorps ptp2c, anticorps ptpn11, anticorps ptpn11-a, anticorps ptpn11-b, anticorps shp-2, anticorps shp2, anticorps fa14b09, anticorps wu:fa14b09, anticorps wu:fi24f03, anticorps zgc:55388, anticorps zgc:63553, anticorps protein tyrosine phosphatase, non-receptor type 11, anticorps protein tyrosine phosphatase, non-receptor type 11 S homeolog, anticorps protein tyrosine phosphatase, non-receptor type 11, a, anticorps protein tyrosine phosphatase, non-receptor type 11, b, anticorps PTPN11, anticorps Ptpn11, anticorps ptpn11.S, anticorps ptpn11a, anticorps ptpn11b
Classe de substances
Viral Protein
Sujet
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Poids moléculaire
68011
ID gène
5781
NCBI Accession
NP_002825 , NP_542168
UniProt
Q06124
Pathways
Signalistation JAK/STAT , Signalisation RTK , TCR Signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Negative Regulation of Hormone Secretion , Carbohydrate Homeostasis , Toll-Like Receptors Cascades , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , VEGFR1 Specific Signals , BCR Signaling , L'effet Warburg
Vus récemment
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