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NFKB1 anticorps (AA 905-909)
NFKB1
Reactivité: Humain
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5689493
Détail du produit anti-NFKB1 anticorps
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Antigène
Voir toutes NFKB1 Anticorps
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Épitope
Tous les épitopes à travers NFKB1 Anticorps.
AA 905-909
Reactivité
Toutes les réactivités sur NFKB1 Anticorps
Humain
Hôte
Toutes les hôtes sur NFKB1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur NFKB1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NFKB1 Anticorps
Cet anticorp NFKB1 est non-conjugé
Application
Tous les applications à travers NFKB1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
This antibody detects endogenous level of total NFκ,B-p105/p50 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogène
NFkB-p105/p50 (Ab-907) antibody was raised against a peptide sequence around aa.905~909 (P-L-S-P-A) derived from Human NFκ,B-p105.
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Alternatives
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Information d'application
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Indications d'application
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store antibody at -20°C for up to one year.
Détails sur NFKB1
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Antigène
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Autre désignation
NFkB p105 / p50 (NFKB1 Produits )
Synonymes
anticorps GKLP, anticorps NKTL, anticorps NTKL, anticorps P105, anticorps TAPK, anticorps TEIF, anticorps TRAP, anticorps EBP-1, anticorps KBF1, anticorps NF-kB1, anticorps NF-kappa-B, anticorps NF-kappaB, anticorps NFKB-p105, anticorps NFKB-p50, anticorps NFkappaB, anticorps p105, anticorps p50, anticorps NF-kB, anticorps NF-KB1, anticorps ebp-1, anticorps kbf1, anticorps nf-kappa-b, anticorps nf-kappaB, anticorps nfkb-p105, anticorps nfkb-p50, anticorps NF-kappaB1, anticorps p50/p105, anticorps BICDR-1, anticorps bicdr1, anticorps ccdc64, anticorps SCY1 like pseudokinase 1, anticorps nuclear factor kappa B subunit 1, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog, anticorps nuclear factor NF-kappa-B p105 subunit, anticorps nucleoporin 107, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, anticorps SCYL1, anticorps NFKB1, anticorps Nfkb1, anticorps nfkb1.L, anticorps CpipJ_CPIJ012236, anticorps Nup107, anticorps nfkb1
Sujet
NF-κ,-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ,-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Poids moléculaire
120 kDa
ID gène
4790
NCBI Accession
NP_001158884
UniProt
P19838
Pathways
Signalisation p53 , Signalisation NF-kappaB , Signalisation RTK , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
Vus récemment
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