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IKBKB anticorps
IKBKB
Reactivité: Humain
ELISA, WB
Hôte: Souris
Monoclonal
10A2
unconjugated
Détail du produit anti-IKBKB anticorps
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Antigène
Voir toutes IKBKB Anticorps
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Reactivité
Toutes les réactivités sur IKBKB Anticorps
Humain
Hôte
Toutes les hôtes sur IKBKB Anticorps
Souris
Clonalité
Toutes les clonalités sur IKBKB Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers IKBKB Anticorps
Cet anticorp IKBKB est non-conjugé
Application
Tous les applications à travers IKBKB Anticorps.
ELISA, Western Blotting (WB)
Immunogène
IKBKB antibody was raised in Mouse using a purified recombinant fragment of IKBKB expressed in E. coli as the immunogen.
Clone
10A2
Isotype
IgG1
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Alternatives
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Information d'application
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Indications d'application
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Détails sur IKBKB
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Antigène
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Autre désignation
IKBKB (IKBKB Produits )
Synonymes
anticorps ikk-beta, anticorps ikk2, anticorps ikkb, anticorps ikkbeta, anticorps IKBKB, anticorps IKKB, anticorps CG4201, anticorps DIK, anticorps DLAK, anticorps DmIKK, anticorps DmIKKBeta, anticorps DmIKKb, anticorps DmIKKbeta, anticorps DmIkkbeta, anticorps Dmel\\CG4201, anticorps Dmikkb, anticorps Dmikkbeta, anticorps IK, anticorps IKK, anticorps IKK-beta, anticorps IKKb, anticorps IKKbeta, anticorps IRD-5, anticorps IRD5, anticorps Ik, anticorps Ikkb, anticorps Ikkbeta, anticorps Ird-5, anticorps Ird5, anticorps LRK, anticorps Lak, anticorps anon-89Bd, anticorps dIKK, anticorps dIKK-beta, anticorps dIKKbeta, anticorps dLak, anticorps dmIKKbeta, anticorps ikk, anticorps ird, anticorps ird5/DmIkk[beta], anticorps IKK2, anticorps NFKBIKB, anticorps AIM-1, anticorps AI132552, anticorps IKK-2, anticorps IKK[b], anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog, anticorps inhibitor of nuclear factor kappa B kinase subunit beta, anticorps I-kappaB kinase beta, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, anticorps inhibitor of kappaB kinase beta, anticorps ikbkb.L, anticorps IKBKB, anticorps ikbkb, anticorps IKKbeta, anticorps Ikbkb
Sujet
IKBKB is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1. Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK-beta activity can also be regulated by MEKK-1. Synonyms: Monoclonal IKBKB antibody, Anti-IKBKB antibody, Inhibitor of kappa light polypeptide gene enhancer in B-cells antibody, Kinase beta antibody, IKK2 antibody, IKKB antibody.
Pathways
Signalisation NF-kappaB , Signalisation RTK , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Production of Molecular Mediator of Immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
Vus récemment
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